Bioinformatics, and expanded sciences – collective disciplines that rely on the use of broad data sets of biological information – present a data management challenge for researchers around the world. Big data gathered as part of research projects and experiments can be complex, with several types of variables involved. Coupled with the dynamic informatics and ever-changing IT tools, there is a need to introduce an interdisciplinary approach in these areas.
Advances in bioinformatics, biostatistics and omic sciences attempt to achieve an integrated approach among all omic sciences, exploring innovative bioinformatics and biostatistics methodologies that enable researchers to uncover the hidden aspects of biological phenomena.
This volume provides reviews on the following topics that provide an overview of recent developments in this area:
- – New integrated mitochondrial DNA bioinformatics pipeline to improve quality assessment of putative pathogen variants from NGS experiments
– Variable recall for RNA sequence data: State of the art and future perspectives
An innovative gene prioritization pipeline for WES analyzes
A novel integrated approach to differential expression of RNA-Seq data analysis
Innovations in data visualization for direct interpretation of DNA Omics results
This volume serves as a guide for graduate students in bioinformatics as well as researchers who are planning new projects as part of their professional and academic activities.
About the author
Dr. Luigi Donato graduated in Biology and completed his PhD in “Applied Biology and Experimental Medicine” at the University of Messina, Italy, where he visits the Molecular Genetics Laboratories of the BIOMORF department. He is a researcher at the Euro-Mediterranean Institute of Science and Technology (IEMEST) in Palermo, Italy, where he is studying a MA in Bioinformatics and Applied Statistics in Sciences. I have published more than 50 papers in prestigious international journals and participated in more than 30 national and international conferences, and I am also a member of the organizing committee of three of them. In addition, he was a member of the “Association for Research in Vision and Ophthalmology” (ARVO) and a member of the “Associazione Italiana di Biologia e Genetica” (AIBG). Most recently, she joined the Editorial Board of BMC Bioinformatics, Cell Cycle, Antioxidants (Guest Editor), Bioinformatics & Proteomics Open Access Journal, and the Board of Reviewers at Brain Sciences. Dr. Donato has also served as a reviewer for more than 15 influential international journals. His main areas of research focus on rare genetic diseases, particularly hereditary retinal dystrophies (IRDs, with retinitis pigmentosa in particular), cerebral cavernous malformations (CCMs), arteriovenous malformations (AVM) and Trimethylaminuria (TMAU).
Bioinformatics, OMIC Sciences, Biostatistics, Data Visualization, IT Tools, Big Data, Data Analysis,
For more information, please visit: https: /